Rolfes Lab
Understanding Cellular Responses to Environmental Conditions
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    • Nutrient sensing and inositol pyrophosphates in Saccharomyces cerevisiae
    • Transcriptional control of hyphae formation in Candida albicans
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My research group and I are interested in how microbial cells sense environmental conditions and how they use that information to change gene expression to affect cell morphology and physiology.  

My group has been focused on nutrient sensing in the model organism Saccharomyces cerevisiae and on the morphological changes in the human pathogenic fungus Candida albicans.  Visit the Research section for more information on our projects. 

My group consists of graduate and undergraduate students who work together on projects employing genetic, biochemical and cell biological approaches to answering research questions. 



Our paper is out!!!  ​Grf10 regulates the response to copper, iron, and phosphate in Candida albicans by Tanaporn Wangsanut, Sylvia J.Y. Arnold, Safia Z. Jilani, Sarah Marzec, Robert C. Monsour, and Ronda J. Rolfes.  It is in press at G3: Genes | Genomes | Genetics   Link Here to the Pre-print Version

Congratulations to Sylvia Arnold!!!  Her PhD dissertation, entitled The Role of Grf10 in Copper, Iron, and Phosphate Homeostasis in Candida albicans, was successfully defended on April 13!  Well done!  

Department of Biology  |  Georgetown University
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